Thursday, November 20, 2008

Should cloning be used to resurrect extinct species?

FROM BLOG: The Conservation Report - The Conservation Report presents the latest environmental news and comment from a moderate perspective. From air pollution to zoonotic diseases and everything else in between.

woolly-mammothmammoth-hair1Should science resurrect extinct species? Some scientists think so. I find megafauna like mammoths and elephant birds fascinating, but I also realize that one of the greatest challenges today is protecting living flora and fauna from human expansion and habitat degradation, loss, and fragmentation—so I don’t know. On one hand it would be remarkable, but then again those resources can be used to conserve living wildlife. From the New York Times, United States:

Scientists are talking for the first time about the old idea of resurrecting extinct species as if this long time staple of science fiction were a realistic possibility, saying that a living mammoth could perhaps be regenerated for as little as $10 million.

The same technology could be applied to any other extinct species from which one can obtain hair, horn, hooves, fur or feathers, and which went extinct within the last 60,000 years. Though the stuffed animals in natural history museums are not likely to burst into life again, these old collections are full of items that may contain ancient DNA which can be decoded by the new generation of DNA sequencing machines.

If the genome of an extinct species can be reconstructed, biologists can work out the exact DNA differences with the genome of its nearest living relative. There are now discussions of how to modify the DNA in an elephant’s egg so that generation by generation it would progressively resemble the DNA in a mammoth egg. The final stage egg could then be brought to term in an elephant mother, and mammoths might once again roam the Siberian steppes. The same would be technically possible with Neanderthals, whose full genome is expected to be recovered shortly, but ethically more challenging.

A scientific team headed by Stephan C. Schuster and Webb Miller at Pennsylvania State University report in today’s issue of Nature that they have recovered a large fraction of the mammoth genome from clumps of mammoth hair. Mammoths were driven to extinction toward the end of the last ice age, some 10,000 years ago, after the first modern humans learned how to survive and hunt in the steppes of Siberia.

No comments: